Hardy-Weinberg Genotype Estimates from Phenotype Counts

Hardy-Weinberg Genotype Estimates from Phenotype Counts

Enter the counts for the dominant and recessive phenotypes. Assuming Hardy-Weinberg equilibrium, the app will estimate allele frequencies and the expected genotype counts and frequencies.

q² = recessive / N   |   q = √q²   |   p = 1 − q   |   AA = p², Aa = 2pq, aa = q²

N = total number of individuals   |   p = frequency of allele A   |   q = frequency of allele a   |   aa is inferred from the recessive phenotype.

Input

Enter phenotype counts to begin.
This estimator assumes Hardy-Weinberg equilibrium. Because the dominant phenotype combines both AA and Aa, those genotypes are estimated rather than observed directly.

Results

N
—
Dominant phenotype frequency
—
Recessive phenotype frequency
—
p
—
q
—
p + q
—
Estimated AA frequency (p²)
—
Estimated Aa frequency (2pq)
—
Estimated aa frequency (q²)
—
Estimated AA count
—
Estimated Aa count
—
Estimated aa count
—
Check pending
These results are estimates under Hardy-Weinberg equilibrium. The recessive phenotype is used to infer q², then q, p, and the expected genotype distribution.